Status:

TERMINATED

Investigating Motor Cortex Processing for Pain Modulation

Lead Sponsor:

Spaulding Rehabilitation Hospital

Conditions:

Motor Activity

Eligibility:

MALE

18-64 years

Phase:

PHASE1

Brief Summary

The purpose of this study is to investigate the effects of different types of interventions (motor learning, somatosensory learning, observation task, mental imagery and tDCS) on the perception of pai...

Detailed Description

There are 5 experiments: Exp1: motor learning (3 groups, crossover) - motor leaning with and without visual feedback and a control group. Exp2: sensory learning (4 groups, parallel) - sensory learni...

Eligibility Criteria

Inclusion

  • Inclusion Criteria
  • Provide informed consent to participate in the study
  • 18 to 64 years old
  • No presence of rheumatologic disease as self reported
  • No clinically significant or unstable medical or psychiatric disorder as self reported
  • No history of alcohol or substance abuse within the last 6 months as self reported
  • No neuropsychiatric co-morbidity as self reported
  • No Contraindications to single pulse TMS (TMS will be used to measure cortical excitability)
  • history of seizures
  • unexplained loss of consciousness
  • metal in the head
  • frequent or severe headaches or neck pain
  • implanted brain medical devices
  • No Contraindications to tDCS
  • metal in the head
  • implanted brain medical devices

Exclusion

    Key Trial Info

    Start Date :

    September 1 2010

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    April 1 2014

    Estimated Enrollment :

    115 Patients enrolled

    Trial Details

    Trial ID

    NCT01404039

    Start Date

    September 1 2010

    End Date

    April 1 2014

    Last Update

    April 24 2020

    Active Locations (1)

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    1

    Spaulding Rehabilitation Hospital

    Boston, Massachusetts, United States, 02114