Status:

COMPLETED

Taste Assessment Study of 2 Atazanavir Powder Formulations in Healthy Subjects

Lead Sponsor:

Bristol-Myers Squibb

Conditions:

HIV

Eligibility:

All Genders

18-49 years

Phase:

PHASE1

Brief Summary

The purpose of this study is to compare the sweetness of 2 new atazanavir powder for oral use (POU) formulations to the current atazanavir POU in healthy participants and to select 1 atazanavir POU th...

Detailed Description

This study is a taste assessment study designed to select a new atazanavir powder for oral use (POU) formulation that is similar in sweetness to the current POU formulation. Participants were to taste...

Eligibility Criteria

Inclusion

  • Key inclusion criteria:
  • Healthy men and women, ages 18 to 49, inclusive
  • Nonsmokers
  • Women not pregnant or breastfeeding
  • Participants who could match solutions of the same sweetness and provide consistent sweetness scores during the taste screening
  • Key exclusion criteria:
  • Any significant acute or chronic medical illness
  • Any acute or chronic condition that may have altered taste sensory perception
  • Any major surgery or trauma within 4 weeks of Day 1
  • Blood transfusion within 4 weeks of study participation
  • Recent (within 6 months of Day 1) drug or alcohol abuse as defined in the Diagnostic and Statistical Manual, 4th edition, Diagnostic Criteria for Drug and Alcohol Abuse
  • Positive urine drug screen
  • Positive urine screen for cotinine
  • Positive hepatitis C antibody, hepatitis B surface antigen, or human immunodeficiency virus antibodies
  • Clinically significant elevations in results of liver function tests above normal range

Exclusion

    Key Trial Info

    Start Date :

    August 1 2011

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    September 1 2011

    Estimated Enrollment :

    12 Patients enrolled

    Trial Details

    Trial ID

    NCT01404572

    Start Date

    August 1 2011

    End Date

    September 1 2011

    Last Update

    June 10 2013

    Active Locations (1)

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    Pra International

    Lenexa, Kansas, United States, 66219