Status:
COMPLETED
Characterization of Transcriptional Regulators of Ghrelin Hormone Which Causes Genetic Obesity
Lead Sponsor:
Samsung Medical Center
Conditions:
Prader Willi Syndrome
Obesity
Eligibility:
All Genders
5-11 years
Brief Summary
The problem point of the Prader-Willi Syndrome (PWS) patient is the obesity which is intense and the plasma ghrelin level which increases unusual from the recently PWS patients was discovered. The Ghr...
Detailed Description
It will reach to respect, in 5 ' -flanking region of the ghrelin 2000 bp focus it let and it got luciferase assay it led and and it searched for the binding it sorted it put out and and to sleep the t...
Eligibility Criteria
Inclusion
- PWS patients were genetically confirmed using the standard methylation test. GHD was diagnosed using a GH stimulation test. The lean and obese normal subjects (comparison group) enrolled were the children or siblings of hospital staff who understood the purpose of and the procedures used.
Exclusion
- GHD patients had no history of GH treatment, and were not being treated with GH at study commencement
Key Trial Info
Start Date :
January 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2006
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT01404624
Start Date
January 1 2005
End Date
December 1 2006
Last Update
July 28 2011
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