Status:

COMPLETED

Clinical Evaluation of a New Transpulmonary Thermodilution Method to Assess Thermodilution Cardiac Output, Global End Diastolic Volume and Extravascular Lung Water

Lead Sponsor:

Edwards Lifesciences

Conditions:

Cardiac Output and Preload Assessment

Lung Water Assessment

Eligibility:

All Genders

18+ years

Brief Summary

The primary objective of this study is to obtain the TPTD, GEDV and EVLW measurements from existing indwelling femoral arterial Volume View™ catheter and central venous catheters.

Detailed Description

Transpulmonary thermodilution has been proposed to measure transpulmonary thermodilution cardiac output (TPTD), preload (GEDV, global end diastolic volume) and to quantify pulmonary edema (EVLW, extra...

Eligibility Criteria

Inclusion

  • Patient must have clinical need for an indwelling femoral arterial catheter and central venous catheter.
  • Patient, or legal guardian, must sign consent to be in the study prior to data capture.
  • Patient must be at least 18 years old.
  • Patient height and weight are available prior to study.

Exclusion

  • Patients with significant aortic valve regurgitation.
  • Patients being treated with an intra-aortic balloon pump.
  • Patients less than 40 kg in weight.
  • Female patients with a known pregnancy or planned pregnancy.
  • Patient is currently participating in an investigational drug or another device study that clinically interferes with the study endpoints.
  • Patients with peripheral vascular disease.
  • Patients with aortic aneurysm.

Key Trial Info

Start Date :

January 1 2010

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2010

Estimated Enrollment :

97 Patients enrolled

Trial Details

Trial ID

NCT01405040

Start Date

January 1 2010

End Date

December 1 2010

Last Update

April 4 2013

Active Locations (4)

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Page 1 of 1 (4 locations)

1

Universitätsklinikum der RWTH Aachen

Aachen, Pauwelsstrasse 30, Germany, 52074

2

Der Rheinischen Friedrich-Wilhelms-Universität Bonn

Bonn, Sigmund Freud Strasse 25, Germany, 53105

3

Stadtspital Triemli Zürich

Zurich, Birmensdorferstr 497, Switzerland, 8063

4

HUG-Hôpitaux Universitalres de Genève

Geneva, Canton of Geneva, Switzerland, 1211