Status:

COMPLETED

Endoscopic Peroral Myotomy for Treatment of Achalasia

Lead Sponsor:

Universitätsklinikum Hamburg-Eppendorf

Conditions:

Achalasia

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

This study intends to investigate the feasibility, safety and efficacy of peroral endoscopic myotomy for the treatment of achalasia in a single center setting in Europe.

Detailed Description

This pilot study intends to investigate the feasibility, safety and efficacy of peroral endoscopic myotomy for the treatment of achalasia in a single center setting in Europe. 16 patients are enrolle...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Patient with symptomatic achalasia and pre-op barium swallow, manometry and esophagal-gastro-duodenoscopy which are consistent with the diagnosis
  • persons of age \> 18 years with medical indication for surgical myotomy or Endoscopic balloon dilatation
  • Signed written informed consent.
  • Exclusion criteria:
  • Patients with previous surgery of the stomach or esophagus
  • Patients with known coagulopathy
  • Previous achalasia-treatment with surgery
  • Patients with liver cirrhosis and/or esophageal varices
  • Active esophagitis
  • Eosinophilic esophagitis
  • Barrett's esophagus
  • Pregnancy
  • Stricture of the esophagus
  • Malignant or premalignant esophageal lesion
  • Candida esophagitis
  • Hiatal hernia \> 2cm

Exclusion

    Key Trial Info

    Start Date :

    November 1 2010

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    November 1 2016

    Estimated Enrollment :

    16 Patients enrolled

    Trial Details

    Trial ID

    NCT01405469

    Start Date

    November 1 2010

    End Date

    November 1 2016

    Last Update

    October 15 2019

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    Universitätsklinikum Hamburg-Eppendorf, Klinik für Interdisziplinäre Endoskopie

    Hamburg, Germany, 20246