Status:
COMPLETED
MRI Study of Tic Remission in Tourette Syndrome
Lead Sponsor:
University of Utah
Conditions:
Tourette Syndrome
Eligibility:
MALE
18-35 years
Brief Summary
Doctors provide a ray of hope to children and their parents with the knowledge that, for most patients, symptoms of Tourette syndrome improve by the time they are young adults. The investigators do no...
Detailed Description
One of the most interesting aspects of Tourette syndrome is a virtual remission of tics by early adulthood in about half of patients. Information is needed to clarify the mechanism of tic remission in...
Eligibility Criteria
Inclusion
- All subjects: males aged 18-35 with history of Tourette syndrome and at least moderately disabling tics during childhood.
- Persistent Tourette's subjects: history of disabling tics during childhood but no longer taking tic suppressing drugs.
- Tic remission subjects: no longer experiencing any disability (even social discomfort) from tics. Must have had sustained improvement of tics for at least 3 years.
- Normal controls: no longer recruiting.
Exclusion
- Tourette's subjects still taking tic suppressing drugs are excluded. Also excluded are any patients with a condition (such as a pacemaker, recent tattoo, implantable metal device, or claustrophobia) that could make the MRI examination unsafe.
Key Trial Info
Start Date :
January 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2012
Estimated Enrollment :
21 Patients enrolled
Trial Details
Trial ID
NCT01405859
Start Date
January 1 2010
End Date
June 1 2012
Last Update
May 12 2016
Active Locations (1)
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1
University of Utah
Salt Lake City, Utah, United States, 84108