Status:
COMPLETED
Monitoring of Delayed Ischemia After Subarachnoid Hemorrhage
Lead Sponsor:
University of Cincinnati
Conditions:
Subarachnoid Hemorrhage
Eligibility:
All Genders
18-70 years
Brief Summary
The goal in this research is to develop better ways to detect and treat the damage caused by bleeding in the brain.
Detailed Description
Patients who suffer from a bleeding in the brain (stroke or hemorrhage) often experience secondary complications that can occur up to 2 weeks after the initial bleeding. Complications can include decr...
Eligibility Criteria
Inclusion
- Age 18 to 70 years
- World Federation of Neurosurgery (WFNS) grade III-IV, and grade V patients who improve within 24h after ventriculostomy
- Diffuse thick or localized thick subarachnoid clot \>1 mm on baseline CT (Fisher grade 3-4)
- Ruptured saccular aneurysm demonstrated by CT-angiography or DSA
- Onset of aSAH clinical symptoms within the preceding 72h
- Treatment of aneurysm within 24 h after admission
- Treatment of aneurysm by clip ligation
Exclusion
- SAH due to other causes (e.g. trauma, fusiform or mycotic aneurysm)
- Only a thin diffuse layer or no visible subarachnoid blood in the initial CT
- Admission in a clinical state with unfavourable prognosis (e.g., bilateral dilated, non-reactive pupils for more than 1h)
- Coagulopathy (thrombocytes \<60,000/ml or INR\>1.5)
- Pregnancy
- Presence of incompatibilities for MRI, such as non-removable metals, artificial joints, electronic devices (pace maker, pumps), etc.
Key Trial Info
Start Date :
June 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
March 1 2014
Estimated Enrollment :
7 Patients enrolled
Trial Details
Trial ID
NCT01406457
Start Date
June 1 2010
End Date
March 1 2014
Last Update
October 21 2015
Active Locations (1)
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1
University of Cincinnati
Cincinnati, Ohio, United States, 45219