Status:
COMPLETED
Conventional Repetitive Transcranial Magnetic Stimulation for Tinnitus Treatment
Lead Sponsor:
Hospices Civils de Lyon
Conditions:
Chronic Tinnitus
Eligibility:
All Genders
18-75 years
Phase:
PHASE1
PHASE2
Brief Summary
The objective of the investigators study is to assess conventional repetitive transcranial magnetic stimulation (rTMS) in patients with chronic severe tinnitus. A randomized, double-blind, sham-contro...
Eligibility Criteria
Inclusion
- Men and women between the ages of 18 and 75 years old;
- Adequate medical condition (ASA P1 or P2 in Physical Status Classification System);
- Disabling tinnitus (STSS \> 8/16 or THQ \> 50%), with the following characteristics: continuous, subjective, non-pulsatile; unilateral (or bilateral with unilateral predominance), chronic (duration for at least one year), refractory for usual treatments taken for at least six months;
- Naive regarding TMS;
- Able to provide informed consent.
Exclusion
- Objective tinnitus or tinnitus with treatable cause;
- Presence of intracranial or intraocular ferromagnetic materiel or particles (with the exception of dental fillings and MRI-compatible stapedectomy prosthesis);
- Cardiac pacemaker or other electronic implants (including cochlear implant);
- Serious heart disease or other unstable major medical condition;
- Personal history of central nervous system disorder, head injury, stroke or seizures (including childhood febrile seizures);
- Familial history of epilepsy;
- Concomitant medication with antidepressants and antipsychotics;
- Possibility of pregnancy;
- Known claustrophobia;
- Others known contraindications to rTMS or brain MRI;
- Refusal to be informed about the results of anatomical MRI
Key Trial Info
Start Date :
May 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2009
Estimated Enrollment :
64 Patients enrolled
Trial Details
Trial ID
NCT01407133
Start Date
May 1 2005
End Date
September 1 2009
Last Update
December 19 2025
Active Locations (3)
Enter a location and click search to find clinical trials sorted by distance.
1
Département d'ORL et de Chirurgie Cervico-Maxillo-Faciale, Hôpital Edouard Herriot
Lyon, France, 69437
2
Service d'Audiologie et Explorations Orofaciales, Centre Hospitalier Lyon Sud
Pierre-Bénite, France, 69495
3
Service d'Oto-Rhino-Laryngologie, Centre Hospitalier Lyon-Sud
Pierre-Bénite, France, 69495