Status:
UNKNOWN
Repair of Articular Osteochondral Defect
Lead Sponsor:
National Taiwan University Hospital
Conditions:
Osteochondritis Dissecans
Eligibility:
All Genders
18-60 years
Phase:
NA
Brief Summary
Background: Matrix-associated autologous chondrocyte implantation (MACI) has been recently used to treat cartilage defects. The investigators had previously developed a biphasic osteochondral composit...
Detailed Description
Methods: Ten patients with symptomatic isolated osteochondritis at the femoral condyle were treated by replacing the pathological tissue with autologous chondrocyte-laden biphasic cylindrical plug of ...
Eligibility Criteria
Inclusion
- Age: 18 \~ 60 years
- Articular cartilage defect of the knee
- Diagnosis by X-ray and/or MRI, Arthroscopy
- Confined area: diameter \< 3 cm
- Full layer cartilage damage
Exclusion
- Pregnancy
- Nonunion of fracture around the knee
- Diffuse degenerative arthropathy of the knee
- Diffuse cartilage pathology due to
- Rheumatism: rheumatoid, psoriatic, …
- Metabolic disorder: gouty, hemorrhagic, …
- Stiff knee from any reason
- Flexion \< 130˚
- Extension loss \> 20˚
Key Trial Info
Start Date :
March 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2011
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT01409447
Start Date
March 1 2009
End Date
December 1 2011
Last Update
August 22 2011
Active Locations (1)
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1
National Taiwan University Hospital
Taipei, Taipei, Taiwan, 100