Status:
TERMINATED
A Multi-Centered Trial Evaluating the Role of Vitamin D Metabolism in Non-Small Cell Lung Cancer
Lead Sponsor:
University of Michigan Rogel Cancer Center
Conditions:
Non-Small Cell Lung Cancer
Eligibility:
All Genders
18-80 years
Brief Summary
Vitamin D exerts antiproliferative and differentiating effects in cancers, including non-small cell lung cancer (NSCLC). The active form of Vitamin D is 1,25, dihydroxycholecalciferol (calcitriol) whi...
Detailed Description
This study seeks to prospectively determine the relationship between Vitamin D gene expression and median survival as a primary outcome, and the relationships between the Vitamin D receptor (VDR)/CYP2...
Eligibility Criteria
Inclusion
- Scheduled for diagnostic bronchoscopy for suspected advanced stage lung cancer by CT/PET scanning.
- Tumor or lymph node accessible by transbronchial needle aspiration.
- Age 18-80.
- All patients must be informed of the investigational nature of this study and must give written informed consent in accordance with institutional and federal guidelines.
Exclusion
- Unstable cardiovascular disease or other systemic disease
- Mental incompetence/active psychiatric illness
- Medical contraindication for bronchoscopy
Key Trial Info
Start Date :
May 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
41 Patients enrolled
Trial Details
Trial ID
NCT01409681
Start Date
May 1 2011
End Date
December 1 2013
Last Update
March 31 2014
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
United States Department of Veteran's Affairs Medical Center
Ann Arbor, Michigan, United States, 48105
2
University of Michigan Cancer Center
Ann Arbor, Michigan, United States, 48109