Status:
WITHDRAWN
Diclofenac add-on to Treatment as Usual for Suicidal Patients
Lead Sponsor:
Region Skane
Conditions:
Depression Suicidal
Eligibility:
All Genders
18-65 years
Phase:
PHASE1
PHASE2
Brief Summary
The purpose of this study is to determine whether diclofenac is effective in the treatment of depressed patients with a recent suicide attempt.
Detailed Description
The study will start with a feasibility study including treatment of 10 patients with diclofenac.
Eligibility Criteria
Inclusion
- Depressive disorder
- Montgomery Asberg Rating Scale Score more than 20 p.
- Recent suicide attempt (Treated as inpatient due to a recent suicide attempt)
- Informed consent
- Competence to give informed consent
Exclusion
- Pregnancy
- Breastfeeding
- Serious somatic disease e.g. serious heart, vascular, hepatic, kidney, pulmonary, intestinal, endocrine, haematological or neurological diseases
- Ongoing substance abuse
- Schizophrenia or other psychotic disorders
- Ongoing psychosis
- Risk factors for cardiovascular events
- Ulcer or gastrointestinal bleeding
- Ongoing Electroconvulsive therapy
- Previous allergic reaction to NSAID, acetylsalicylic acid, sulfonamides or the diclofenac or sugar pill content
- Galactose intolerance, lactase deficiency or glucose-galactose malabsorption
- Ongoing treatment with warfarin or other anticoagulants
- Ongoing treatment with ACE inhibitors or angiotensin II antagonists Ongoing treatment with drugs known to effect the immune system Ongoing treatment with rifampicin, carbamazepine or barbiturates
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01413854
Start Date
August 1 2011
End Date
August 1 2011
Last Update
January 10 2019
Active Locations (1)
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1
Psychiatry Skane
Lund, Sweden