Status:
TERMINATED
Ileocecal Sphincter Reflex by Cecal Distension During Colonoscopy
Lead Sponsor:
Northwell Health
Conditions:
Irritable Bowel Syndrome
Eligibility:
All Genders
20-80 years
Brief Summary
The aim of the current study is to test the hypothesis that patients with IBS may have a defective ICV pressures and may have small bowel bacterial overgrowth. The goal of the current study is to iden...
Detailed Description
This is an outpatient study. There will be no requirement to stay overnight in the hospital. The research will be conducted in the gastroenterology section of the department of Medicine in North shore...
Eligibility Criteria
Inclusion
- Patients with a history of small bowel bacterial overgrowth or irritable bowel syndrome and who are undergoing routine colonoscopies or subjects who are undergoing routine colonoscopy and test positive for small bowel bacterial overgrowth will be candidates. If the patient has prior lactulose breath test done for clinical purposes then repeat lactulose breath test will not be required. If no prior lactulose breath test has been performed then it will be done as part of this research study. In addition patients who test negative for SBBO will be candidates for the control population.
Exclusion
- Medications-Subjects on any medication that could affect the ileocecal valve high-pressure zone will be excluded; this includes use of prokinetic agents, current use of any antibiotics and anticholinergics. Patients will be excluded if the lactulose breath test is done on antibiotics or during the colonoscopy preparation.
- GI symptoms, conditions and disorders: In addition exclusion criteria will include a history of ileocecal resection or disease affecting the colon and/or small bowel including crohn's disease, ulcerative colitis or diseases causing diarrhea.
Key Trial Info
Start Date :
June 21 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 18 2017
Estimated Enrollment :
2 Patients enrolled
Trial Details
Trial ID
NCT01413945
Start Date
June 21 2013
End Date
January 18 2017
Last Update
February 22 2019
Active Locations (1)
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1
LIJ Medical Center- NSLIJ Health System
New Hyde Park, New York, United States, 11040