Status:
COMPLETED
Life After Pediatric Sepsis Evaluation
Lead Sponsor:
Seattle Children's Hospital
Collaborating Sponsors:
The National Collaborative Pediatric Critical Care Research Network
Children's Hospital Los Angeles
Conditions:
Septic Shock
Eligibility:
All Genders
1-18 years
Brief Summary
Sepsis represents the leading cause of childhood mortality worldwide. However, as distinct from adult medicine, there exists a large knowledge gap regarding long term health related quality of life (H...
Detailed Description
In-hospital pediatric sepsis mortality has decreased substantially, but long-term mortality and morbidity among children initially surviving sepsis, is unknown. Accordingly, the Life After Pediatric S...
Eligibility Criteria
Inclusion
- Age 44 weeks EGA to 18 years
- Admitted to the PICU for the sepsis event
- Evidence of SIRS including fever/ hypothermia and leukocytosis/leukopenia
- Documented or suspected infection
- Cardiovascular organ dysfunction with need for vasoactive-inotropic support
Exclusion
- Lack of commitment to aggressive sepsis therapy OR
- Ward of the state OR
- Sepsis event associated with a PICU-acquired nosocomial infection OR
- Parents do not speak English or Spanish OR
- Previously enrolled in the LAPSE study
- Enrollment not possible within 12 hours of PICU admission
Key Trial Info
Start Date :
June 1 2013
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2018
Estimated Enrollment :
389 Patients enrolled
Trial Details
Trial ID
NCT01415180
Start Date
June 1 2013
End Date
June 1 2018
Last Update
December 6 2022
Active Locations (11)
Enter a location and click search to find clinical trials sorted by distance.
1
Phoenix Children's Hospital
Phoenix, Arizona, United States
2
Children's Hospital of Los Angeles
Los Angeles, California, United States
3
Mattel Children's Hospital
Los Angeles, California, United States
4
National Children's Hospital
Washington D.C., District of Columbia, United States