Status:
COMPLETED
Nutrient Synergy in Beef and Stimulation of Protein Synthesis in Elderly
Lead Sponsor:
University of Arkansas
Conditions:
Healthy
Eligibility:
All Genders
60+ years
Phase:
NA
Brief Summary
This study will compare the effects of cooked, ground beef to those of beef protein isolate on blood and muscle proteins.
Detailed Description
STUDY OBJECTIVES Primary: To compare the effects of consumption of a 3-ounce serving of beef to that of a 20g serving of BPI on skeletal muscle synthetic and breakdown rate in healthy elderly subjects...
Eligibility Criteria
Inclusion
- Healthy male or female.
- Age 60 years or older.
Exclusion
- Any (history of) gastrointestinal disease that interferes with GI function
- Diagnosed and active treatment of Diabetes Mellitus type I or II
- History of congestive heart failure
- Recent (6 months) hospitalization for heart disease treatment or management (e.g. PTCA, stent, surgery)
- Myocardial infarction in the past year
- Infection or fever in the 7 days prior to enrollment
- Current use of corticosteroids, growth hormone, or testosterone
- Adherence to a weight loss diet
- Use of protein-containing or amino acid-containing nutritional supplements within one week of enrollment
- Current alcohol (\>7 ETOH per week) or drug abuse
- Platelet count (PLT) \< 100,000
- History of hypo- or hyper-coagulation disorders including use of a coumadin derivative
- Currently taking anti-thrombotics and cannot stop for 7 days (i.e. medical indication)
- Allergy to local anesthetic
- Blood hemoglobin \< 9.0 g/dL
- Investigator's uncertainty about the willingness or ability of the subject to comply with the protocol requirements
Key Trial Info
Start Date :
July 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2012
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01415973
Start Date
July 1 2011
End Date
January 1 2012
Last Update
January 18 2012
Active Locations (1)
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1
UAMS Center on Aging
Little Rock, Arkansas, United States, 72205