Status:
WITHDRAWN
Vitamin D and Chronic Obstructive Lung Disease
Lead Sponsor:
Jorgen Vestbo
Conditions:
Chronic Obstructive Lung Disease
Eligibility:
All Genders
50+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to examine the effect of vitamin D intervention in patients with chronic obstructive pulmonary disease (COPD) undergoing rehabilitation.
Eligibility Criteria
Inclusion
- Age ≥ 50 years
- Diagnosed COPD with forced expiratory volume in 1 second (FEV1) \< 50 % of predicted
- Breathlessness relative to MRC dyspnoea grade 3 or more
Exclusion
- Patients with known diseases of bone metabolism apart from osteoporosis and patients with granulomatous disease
- Patients with hyper- or hypocalcemia at inclusion
- Patients with cardiovascular or musculoskeletal disease that impacts significantly on walking based on the investigator's judgement
- Patients with dementia or other mental conditions rendering them unable to understand the study information and thus provide informed consent
- Patients with terminal disease or known cancer with bone metastases, increasing their risk of hypercalcemia
- Patients taking more than 20 mcg vitamin D on a daily basis. If a patient takes vitamin D below this limit, dose should have been stable 6 months prior to inclusion in order to achieve steady-state.
- Pregnancy
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT01416701
Start Date
September 1 2011
End Date
December 1 2013
Last Update
April 9 2013
Active Locations (2)
Enter a location and click search to find clinical trials sorted by distance.
1
Hvidovre University Hospital, Department of Respiratory Medicine
Hvidovre, Denmark, 2650
2
Medical Unit, Hvidovre University Hospital
Hvidovre, Denmark, 2650