Status:
UNKNOWN
Renal Sympathetic Modification in Patients With Essential Hypertension
Lead Sponsor:
The Second Affiliated Hospital of Chongqing Medical University
Collaborating Sponsors:
Jiangsu Provincial People's Hospital
Zunyi Medical College
Conditions:
Essential Hypertension
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
The purpose of this study is to observe the incident of composite cardiovascular events after renal sympathetic modification using THERMOCOOL® catheter in patients with essential hypertension, and eva...
Detailed Description
Hypertension is a common cardiovascular disease, and is also an important risk factor for heart-brain-renal diseases, with relatively low controlled rate. Traditional pharmacological therapies are use...
Eligibility Criteria
Inclusion
- ≥ 18 years old, and ≤ 75 years old of age
- more than half a year history of hypertension, except for valvular heart disease
- recently at least three times office blood pressure suggest systolic blood pressure of 140mmHg or more and/or a diastolic blood pressure of 90mmHg or more
- estimated glomerular filtration rate (eGFR) of ≥ 45mL/min
- is competent and willing to provide written, informed consent to participate in this clinical study
Exclusion
- secondary hypertension
- isolated systolic hypertension
- estimated glomerular filtration rate (eGFR) of \< 45mL/min
- has the history of renal restenosis or renal stents implantation
- has experienced AMI (old myocardial infarction is not excluded), unstable angina pectoris, cerebrovascular accidents, and alimentary tract hemorrhage within 3 months
- patients with sick sinus syndrome
- pregnant women
- mental disorders
- patients that have allergy to contrast agent
- patients that do not go with follow-up
- others such as researcher considers it is not appropriate to be included into the study
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
December 1 2020
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01417221
Start Date
August 1 2011
End Date
December 1 2020
Last Update
March 19 2019
Active Locations (1)
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1
2ndChongqingMU
Chongqing, Chongqing Municipality, China, 400010