Status:
UNKNOWN
Impact of Vitamin A on Multiple Sclerosis (MS)
Lead Sponsor:
Tehran University of Medical Sciences
Conditions:
Relapsing Remitting Multiple Sclerosis
Eligibility:
All Genders
20-45 years
Phase:
PHASE4
Brief Summary
The aim of this study is the comparison between the effects of supplementation with 25000 IU preformed vitamin A (retinyl palmitate) or placebo for first 6 months and 10000 IU/day for next 6 months on...
Detailed Description
Multiple Sclerosis (MS) is a chronic inflammatory disease where Th1 like responses from myelin-specific CD4+ T cells, as secretion of pro-inflammatory IFNγ, are believed to play a major role in the pa...
Eligibility Criteria
Inclusion
- Patients who have used interferon beta in last 3 months
- Patients with 0-5 EDSS
Exclusion
- Patients who have diseases which affect on Th1/Th2 balance such as asthma, active viral infections, and autoimmune diseases, OR
- Patients who have allergy to vitamin A compounds, OR
- Patients who have used vitamin supplements in last 3 months.
Key Trial Info
Start Date :
February 1 2010
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
August 1 2013
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01417273
Start Date
February 1 2010
End Date
August 1 2013
Last Update
August 16 2011
Active Locations (1)
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1
Tehran University of Medical Sciences,
Tehran, Iran, School of Public Health