Status:
COMPLETED
Disturbances in BCAA Metabolism and the Effects of Feeding and Exercise in COPD
Lead Sponsor:
Maastricht University Medical Center
Collaborating Sponsors:
European Dairy Association (EDA), Brussels
Conditions:
Chronic Obstructive Pulmonary Disease
Eligibility:
MALE
45+ years
Phase:
NA
Brief Summary
Studies on resting human muscle show that ingestion of the branched-chain amino acids (BCAA): leucine, valine and isoleucine have an anabolic effect on muscle protein metabolism. However, the effects ...
Detailed Description
In this study we investigate whether milk based protein sources of BCAA (casein and whey proteins) are superior to soy protein in the stimulation of protein anabolism before, during and after cycle ex...
Eligibility Criteria
Inclusion
- Irreversible chronic airflow limitation (FEV1 \<70% of predicted)
- Clinically stable condition
Exclusion
- Oxygen supplementation
- Respiratory tract infection or exacerbation of his disease at least 4 weeks prior to the study
- Oral corticosteroids as maintenance medication
- Other concomitant metabolic disease (ie malignancy, cardiac failure, recent surgery, severe endocrine, hepatic or renal disorder)
Key Trial Info
Start Date :
December 1 2002
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2004
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT01418469
Start Date
December 1 2002
End Date
December 1 2004
Last Update
August 17 2011
Active Locations (1)
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1
Maastricht UMC
Maastricht, Netherlands