Status:

COMPLETED

Biomarker Study of Chemotherapy Resistance and Outcomes in Samples From Older Patients With Acute Myeloid Leukemia

Lead Sponsor:

Eastern Cooperative Oncology Group

Collaborating Sponsors:

National Cancer Institute (NCI)

Conditions:

Leukemia

Eligibility:

All Genders

61-120 years

Brief Summary

RATIONALE: Studying blood samples from patients with cancer in the laboratory may help doctors learn more about changes that occur in DNA and identify biomarkers related to cancer. PURPOSE: This rese...

Detailed Description

OBJECTIVES: * Delineate the spectrum of genetic and epigenetic lesions occurring in elderly patients with acute myeloid leukemia (AML). * Determine the biological functions perturbed by these lesions...

Eligibility Criteria

Inclusion

  • DISEASE CHARACTERISTICS:
  • Subset of patients diagnosed with acute myeloid leukemia (AML) enrolled on E3999
  • AML resistant or sensitive to chemotherapy
  • Mononuclear cell samples available
  • PATIENT CHARACTERISTICS:
  • Not specified
  • PRIOR CONCURRENT THERAPY:
  • See Disease Characteristics

Exclusion

    Key Trial Info

    Start Date :

    August 17 2011

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    October 17 2011

    Estimated Enrollment :

    257 Patients enrolled

    Trial Details

    Trial ID

    NCT01421875

    Start Date

    August 17 2011

    End Date

    October 17 2011

    Last Update

    May 17 2017

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