Status:
COMPLETED
Sorbent Therapy of the Cutaneous Porphyrias
Lead Sponsor:
Brigham and Women's Hospital
Conditions:
Erythropoietic Protoporphyria
Eligibility:
All Genders
22-60 years
Phase:
PHASE2
PHASE3
Brief Summary
The investigators demonstrated that cholestyramine is an effective binding agent in vitro for porphyrins. A few isolated case reports of treatment of individuals with a cutaneous porphyria suggest tha...
Detailed Description
Four adults with proven EPP volunteered as subjects for this study. First period: Subjects received 1 gm colestipol twice daily for \~45 days, then 2 gm twice daily for \~45 days. Labs included CBC; l...
Eligibility Criteria
Inclusion
- Adult over age 21
- healthy
Exclusion
- Intercurrent illness
- pregnancy
Key Trial Info
Start Date :
May 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2012
Estimated Enrollment :
4 Patients enrolled
Trial Details
Trial ID
NCT01422915
Start Date
May 1 2011
End Date
March 1 2012
Last Update
April 25 2017
Active Locations (1)
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1
Brigham & Women's Hospital
Boston, Massachusetts, United States, 02115