Status:
COMPLETED
Effect of Lipopolysaccharide on Skeletal Muscle Functions
Lead Sponsor:
University of Nottingham
Conditions:
Sepsis
Eligibility:
MALE
18-30 years
Phase:
NA
Brief Summary
The investigators aim to examine how the skeletal muscles of the human volunteers respond to experimental septic conditions to aid understanding of muscle wasting and its biology.. Six healthy men ag...
Detailed Description
During sepsis, the ability of the body to prevent muscle wasting is impaired resulting in loss of skeletal muscle. In addition, skeletal muscle handling of carbohydrate becomes less efficient. These c...
Eligibility Criteria
Inclusion
- Male 18-30yrs
Exclusion
- Clotting disorders Metabolic disease e.g. diabetes, thyroid dysfunction Inflammatory conditions e.g. Crohn's Disease Tobacco smoker Cardiac or Renal pathology Respiratory problems including Asthma Active infectious conditions
Key Trial Info
Start Date :
July 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
6 Patients enrolled
Trial Details
Trial ID
NCT01423968
Start Date
July 1 2011
End Date
December 1 2012
Last Update
March 27 2018
Active Locations (1)
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1
Queens Medical Centre
Nottingham, Nottinghamshire, United Kingdom, NG7 2UH