Status:
UNKNOWN
A Novel Approach to Endometrial Preparation in Recipients of Donor Eggs
Lead Sponsor:
Kelly, Maureen, M.D.
Collaborating Sponsors:
Merck Sharp & Dohme LLC
Conditions:
Implantation, Embryo
Eligibility:
FEMALE
18-52 years
Phase:
NA
Brief Summary
This study compares two different methods to prepare the uterine lining of recipients for implantation in cycles using donor eggs. The study method requires less time than the standard method. It is ...
Detailed Description
Currently a combination of medications is used to prepare the uterine lining of recipients for implantation in egg donor cycles. The protocol used most commonly is as follows: Initially the individual...
Eligibility Criteria
Inclusion
- recipients awaiting egg donation
- some ovarian function
- normal endometrial cavity
Exclusion
- submucosal myoma
- myoma(s) greater than 4 centimeters
- endometrial polyp
- DES exposure
- documented recalcitrant thin endometrium ( \<7 mm)
- untreated vulvovaginitis
- active pelvic infection
- endometrial cancer or suspected/known hormonally sensitive cancers
- breast cancer
- thromboembolic disease
- cerebrovascular or coronary heart disease
- diabetes mellitus
- hepatic tumors or active liver disease
- severe hypertension
- headaches with neurologic disease
- cholestatic disease
- heavy smoking over age 35
Key Trial Info
Start Date :
January 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT01424618
Start Date
January 1 2006
Last Update
August 29 2011
Active Locations (1)
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1
Society Hill Reproductive Medicine
Philadelphia, Pennsylvania, United States, 19107