Status:
UNKNOWN
The Effects of Vitamin B-6 Status on Homocysteine, Oxidative Stress, One-carbon Metabolism and Methylation: Cross-section, Case-control, Intervention and Follow-up Studies in Colorectal Cancer
Lead Sponsor:
Taichung Veterans General Hospital
Conditions:
Colorectal Cancer
Eligibility:
All Genders
18-85 years
Phase:
PHASE2
PHASE3
Brief Summary
Vitamin B-6, folate and homocysteine may play a critical role in the colorectal cancer progression. This is a 4-y study and the specific aims are: 1) to compare vitamin B-6, folate and homocysteine st...
Eligibility Criteria
Inclusion
- Colorectal cancer participants were identified by colonoscopy to have at least one historically confirmed colorectal cancer.
Exclusion
- Age\<18 years
- Pregnant women
- Had a history of colorectal cancer
- Attenuated adenomatous polyposis coli
- Inflammatory bowel disease or were taking any medication which could influence homocysteine, folate, vitamin B6 and B12 status, such as H2 blockers, Proton pump inhibitors, metformin, phenytoin, methotrexates.
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 1 2015
Estimated Enrollment :
300 Patients enrolled
Trial Details
Trial ID
NCT01426490
Start Date
August 1 2011
End Date
July 1 2015
Last Update
February 19 2014
Active Locations (1)
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1
Taichung Verterans General Hospital
Taichung, Taiwan