Status:

COMPLETED

Dietary Protein Sources and Atherogenic Dyslipidemia

Lead Sponsor:

UCSF Benioff Children's Hospital Oakland

Collaborating Sponsors:

National Institutes of Health (NIH)

National Heart, Lung, and Blood Institute (NHLBI)

Conditions:

Cardiovascular Disease

Dyslipidemia

Eligibility:

All Genders

30-65 years

Phase:

NA

Brief Summary

There is growing epidemiological evidence that consumption of red meat is associated with greater incidence of Cardiovascular Disease (CVD) than either white meat or non-meat foods. Research from our ...

Detailed Description

Clinic Visits: Participants will visit the clinic a total of 11 times from screen to completion of study. This will include weekly visits with the nutritionist and 9 visits requiring blood draws (at ...

Eligibility Criteria

Inclusion

  • 30-65 years old
  • Non-smoking
  • Agrees to abstain from alcohol and dietary supplements during the study
  • Willing to consume all study foods as instructed

Exclusion

  • History of heart disease, cerebrovascular disease, peripheral vascular disease, bleeding disorder, liver or renal disease, lung disease, diabetes, Human immunodeficiency virus (HIV), or cancer (other than skin cancer) in the last 5 years
  • Body mass index (BMI) \> 35 kg/m2 or \< 20 kg/m2
  • Not weight stable
  • Abnormal thyroid stimulating hormone
  • Blood pressure \> 150/90
  • Fasting blood sugar \>126 mg/dl
  • Fasting triglyceride levels \>500 mg/dl
  • Total- and LDL cholesterol \>95th percentile for age and sex
  • Pregnant or breastfeeding
  • Taking hormones or drugs known to affect lipid metabolism

Key Trial Info

Start Date :

January 1 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 1 2017

Estimated Enrollment :

113 Patients enrolled

Trial Details

Trial ID

NCT01427855

Start Date

January 1 2012

End Date

May 1 2017

Last Update

November 24 2020

Active Locations (1)

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1

Cholesterol Research Center, Children's Hospital Research Institute

Berkeley, California, United States, 94705