Status:
COMPLETED
A Study to Assess the Effects of Multiple-Dose Probenecid on the Multiple-Dose Pharmacokinetics of Canagliflozin in Healthy Volunteers
Lead Sponsor:
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Conditions:
Healthy
Eligibility:
All Genders
15-55 years
Phase:
PHASE1
Brief Summary
The purpose of this study is to assess the effects of multiple doses of probenecid on the multiple-dose pharmacokinetics of canagliflozin and its metabolites in healthy volunteers. Safety and tolerabi...
Detailed Description
This will be a single-center, open-label (identity of study treatments will be known to volunteers participating in the study as well as to study staff) study to assess the effects of multiple doses o...
Eligibility Criteria
Inclusion
- Body mass index (BMI) between 18 and 28 kg/m² inclusive and a body weight of not less than 50 kg.
Exclusion
- History of or current medical illness, abnormal values for hematology or clinical chemistry laboratory tests, or abnormal physical examination, vital signs or 12-lead electrocardiogram (ECG) deemed to be clinically significant by the Investigator
Key Trial Info
Start Date :
August 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT01428284
Start Date
August 1 2011
End Date
October 1 2011
Last Update
February 17 2012
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Overland Park, Kansas, United States