Status:
COMPLETED
Pharmacogenetic Study of Different Hormone Therapies in Recent Menopause Women
Lead Sponsor:
Denusa Wiltgen
Collaborating Sponsors:
Hospital de Clinicas de Porto Alegre
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior.
Conditions:
Postmenopause
Eligibility:
FEMALE
42-58 years
Phase:
NA
Brief Summary
This is cross-over, randomized clinical trial, with objective to evaluate the effects of low-dose oral hormone therapy and non-oral hormone therapy on endothelial function markers (fibrinogen, von Wil...
Eligibility Criteria
Inclusion
- Inclusion criteria:
- last menstrual period between 6 months and 3 years before the beginning of the study plus FSH levels higher than 35 IU/L;
- age between 42 and 58 years;
- no use of any medication known to interfere with hormonal, glucose, or lipoprotein levels in the past 3 months;
- no use of steroidal or no steroidal anti-inflammatory drugs in the last 15 days.
- Exclusion criteria:
- patients with diabetes,
- previous hysterectomy,
- endometrial thickness \>0.5cm,
- history of cancer,
- thromboembolism, or
- established cardiovascular disease
Exclusion
Key Trial Info
Start Date :
March 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2011
Estimated Enrollment :
90 Patients enrolled
Trial Details
Trial ID
NCT01432028
Start Date
March 1 2007
End Date
April 1 2011
Last Update
January 27 2014
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Hospital de Clínicas de Porto Alegre
Porto Alegre, Rio Grande do Sul, Brazil