Status:
COMPLETED
Provitamin A Absorption and Conversion With Avocados
Lead Sponsor:
Ohio State University
Collaborating Sponsors:
Hass Avocado Board
Conditions:
Healthy
Eligibility:
All Genders
18-70 years
Phase:
NA
Brief Summary
Vitamin A is necessary in the human diet. The form of vitamin A found in fruits and vegetables is not "active" and must be converted to the active form in the human body. However, information on the a...
Detailed Description
The primary objective of this study will be to demonstrate that adding avocados to a carotene rich meal will promote the absorption of provitamin A carotenoids and enhance the delivery of greater quan...
Eligibility Criteria
Inclusion
- Total cholesterol (140 to 200 mg/dL)
- BMI 17 to 30
- Age 18-70 years
Exclusion
- Lactating, pregnant, or plan to be pregnant during study
- Tobacco use (cigarettes or chewing tobacco)
- Metabolic disease
- Malabsorption disorders
- History of cancer, esophageal, gastric, or intestinal ulcers
- History of liver or kidney insufficiency or failure
- Allergies to tomatoes or tomato products
- Allergies to carrots
- Allergies to avocados
- Obesity (BMI\>30)
- Hypercholesterolemia (total cholesterol\> 200mg/dL)
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
March 1 2012
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT01432210
Start Date
September 1 2011
End Date
March 1 2012
Last Update
September 30 2016
Active Locations (1)
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1
The Ohio State University Clinical Research Center
Columbus, Ohio, United States, 43210