Status:
COMPLETED
The Efficacy of Aspirin in the Postoperative Period in Vascular Surgery
Lead Sponsor:
University of Lausanne Hospitals
Conditions:
Aspirin Resistance
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to determine the incidence of aspirin resistance in the population of vascular surgery patients; and to evaluate the changes in the efficacy of aspirin in the first five p...
Detailed Description
About 15% of the general population shows resistance to the antiplatelet effects of aspirin, due to genetic polymorphisms and other factors. This resistance is a cause of increased myocardial infarcti...
Eligibility Criteria
Inclusion
- Patient undergoing peripheral vascular or abdominal aorta surgery.
- Patient aged 18 years or older.
- Patient treated by aspirin.
Exclusion
- Incapacity to understand and consent to study.
- Patient undergoing emergency surgery.
- Patient treated by a cox-inhibitor other than aspirin.
- Patient treated by omega-3-fatty acids.
- Patient treated by ADP or GPIIb/IIIa receptor inhibitor.
- Known coagulopathy, thrombopenia, thrombopathia or congenital or acquired thrombasthenia.
- Terminal renal insufficiency.
- Hepathic insufficiency.
Key Trial Info
Start Date :
September 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
May 1 2014
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT01432652
Start Date
September 1 2011
End Date
May 1 2014
Last Update
July 29 2015
Active Locations (1)
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1
University of Lausanne Hospitals
Lausanne, Canton of Vaud, Switzerland, 1011