Status:
COMPLETED
Physiologic Effects of Sleep Restriction
Lead Sponsor:
Mayo Clinic
Conditions:
Sleep Deprivation
Eligibility:
All Genders
18-40 years
Phase:
NA
Brief Summary
Evidence suggests a relationship between sleep deprivation and cardiovascular disease. The investigators wish to determine whether 9 nights of modest sleep restriction results in activation of cardiov...
Detailed Description
Evidence suggests a relationship between sleep deprivation and cardiovascular disease. Voluntary sleep restriction is common, with 28% of the US adult population reports getting 6 or fewer hours of sl...
Eligibility Criteria
Inclusion
- Age 18-40 years
- No chronic medical conditions other than seasonal or environmental allergies
- On no prescription medications other than second generation antihistamines (Cetirizine, Fexofenadine, Desloratadine, Loratadine, etc), oral contraceptive pills, or intrauterine devices.
- BMI 18.5-35 kg/m2
- Both normotensive and prehypertensive people are eligible and will be studied
- Not a current smoker or tobacco user
- Not pregnant or breast feeding and not intending to become pregnant or breast feed
Exclusion
- The investigators will exclude subjects who have any medical or psychiatric disorders
- History of anxiety or depression, and those taking any medications other than non-sedating antihistamines or oral contraceptives.
- Those found to have depression on a depression screening tool (BDI-II) will be excluded. Current smokers will be excluded.
- All female subjects will undergoing a screening pregnancy test and excluded if positive.
- Subjects found to have significant sleep disorders will be excluded.
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 27 2017
Estimated Enrollment :
26 Patients enrolled
Trial Details
Trial ID
NCT01433315
Start Date
October 1 2011
End Date
April 27 2017
Last Update
January 20 2022
Active Locations (1)
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1
Mayo Clinic
Rochester, Minnesota, United States, 55905