Status:

UNKNOWN

Antiretroviral Treatment Strategies in Relation to Adherence, Resistance and Virological Treatment Failure

Lead Sponsor:

Karolinska Institutet

Collaborating Sponsors:

Hanoi Medical University

Conditions:

Human Immunodeficiency Virus (HIV)

Eligibility:

All Genders

18-59 years

Phase:

NA

Brief Summary

This project aims to assess different antiretroviral treatment strategies, optimally controlled and conventional, in relation to drug resistance and virological treatment failure. A Randomised Control...

Detailed Description

Aim To study the impact of patient support on selective drug pressure, defined by semi-quantitative assessments of adherence, on the viral suppression and resistance development through a randomised c...

Eligibility Criteria

Inclusion

  • WHO stage IV of HIV disease, regardless of the CD4 count
  • WHO stage III of HIV disease with a CD4 count \< 350/mm3
  • WHO stages I or II with a CD4 count \< 200/mm3

Exclusion

  • Pregnancy
  • Ongoing severe opportunistic infections
  • Institutionalized patients.

Key Trial Info

Start Date :

August 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2011

Estimated Enrollment :

640 Patients enrolled

Trial Details

Trial ID

NCT01433601

Start Date

August 1 2007

End Date

November 1 2011

Last Update

September 14 2011

Active Locations (1)

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Hanoi Medical University

Hanoi, Hanoi, Vietnam, 01