Status:
UNKNOWN
Prospective Analysis Of Cardiac Function In Cirrhotic Patients By Echocardiography And Its Correlation With Events
Lead Sponsor:
Rio de Janeiro State University
Conditions:
Liver Cirrhosis
Eligibility:
All Genders
18-80 years
Brief Summary
The cardiac abnormalities in patients with cirrhosis are already reported from the 50's, in studies of patients with alcoholic cirrhosis. Further studies have shown that these cardiac changes were cau...
Eligibility Criteria
Inclusion
- Patients with cirrhosis of any etiology, diagnosed by clinical criteria and ultrasound and / or liver biopsy, which excluded patients with causes that also may affect cardiac function (hemochromatosis, Wilson disease, amyloidosis).
- Age between 18 and 80 years.
- Signing of written informed consent.
Exclusion
- History or presence of systemic arterial hypertension (treated or not)
- History or presence of ischemic heart disease and peripheral vascular disease.
- Presence of greater than mild valvular disease.
- Patients who have a different rhythm in the baseline electrocardiogram, other than sinus (atrial fibrillation, atrial flutter, junctional rhythm).
- Presence of severe anemia (Hb \<7 g / dL).
- Presence of shock, hepatic encephalopathy, bacterial infection or bleeding at inclusion or during the previous week.
- History or presence of severe or decompensated lung disease.
- Presence of percutaneous intrahepatic porto-systemic shunt (TIPS).
- Pregnancy.
Key Trial Info
Start Date :
June 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT01433848
Start Date
June 1 2011
Last Update
September 14 2011
Active Locations (1)
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1
Universidade do Estado do Rio de Janeiro
Rio de Janeiro, Rio de Janeiro, Brazil, 20551030