Status:
COMPLETED
Exertional Heat Illness: Biomarkers for Prediction and Return to Duty
Lead Sponsor:
Henry M. Jackson Foundation for the Advancement of Military Medicine
Conditions:
Heat Illness
Eligibility:
All Genders
18-45 years
Brief Summary
The investigators goal is to monitor and quantify the differential physiologic and biomarker responses of controls to standardized exercise under thermoneutral and thermally challenged conditions and ...
Detailed Description
Purpose: Our goal is to monitor and quantify the differential physiologic and biomarker responses of controls to standardized exercise under thermoneutral and thermally challenged conditions and respo...
Eligibility Criteria
Inclusion
- Federal Civilian Employee, Active Duty, or DoD Beneficiary
- Between the ages of 18 and 45 years
- Waist circumference ≤ 39.4 inches (100 cm)
- Willing to walk/run on a treadmill
- Willing to undergo exposure in a thermal chamber
- Willing to maintain their current activity patterns, and to abstain from alcohol, caffeine, and tobacco for 24 hours prior to all sessions
- For cases who have suffered from a exertional heat illness / exertional heat stroke, must have a clinically documented heat stroke within the past year
Exclusion
- History of malignant hyperthermia
- Pregnant or lactating
- Have overt heart disease
- Have systolic blood pressure over 140 mm Hg, or diastolic pressure over 90 mm Hg
- Have a waist circumference \> 39.4 inches (100 cm)
- Are older than 45 or younger than 18 years of age
- Are anemic
- Are taking psychotropic medication for any mental health disorder
- Are taking other selected medications (glucose lowering, prednisone or beta blockers)
Key Trial Info
Start Date :
July 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2016
Estimated Enrollment :
148 Patients enrolled
Trial Details
Trial ID
NCT01434979
Start Date
July 1 2011
End Date
February 1 2016
Last Update
October 11 2019
Active Locations (2)
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1
Uniformed Services University of the Health Sciences
Bethesda, Maryland, United States, 20814
2
Heller Institute of Medical Research
Tel Litwinsky, Israel