Status:

COMPLETED

Robot-assisted Gait Training in Multiple Sclerosis Subjects

Lead Sponsor:

University Hospital of Ferrara

Collaborating Sponsors:

Azienda Ospedaliero, Universitaria Pisana

Conditions:

Multiple Sclerosis

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Aims of the study: This is a randomized-controlled trial to test the effects of robot-assisted gait training on locomotor function and motor unit firing rate in multiple sclerosis subjects with sever...

Eligibility Criteria

Inclusion

  • males and females, community dwelling, age 18 or older
  • diagnosis of multiple sclerosis in a stable phase, with relapses \> 6 months prior to study enrollment
  • moderate to severe gait impairments referred to Expanded Disability Status Scale (EDSS) between 6 and 7

Exclusion

  • neurologic conditions in addition to multiple sclerosis that may affect motor function
  • medical conditions likely to interfere with the ability to safely complete the study
  • impaired cognitive functioning: Mini Mental Status Examination \< 24
  • severe lower-extremities spasticity or contractures that may limit range of motion(Ashworth score \>4 for hip, knee or ankle flexors/extensors

Key Trial Info

Start Date :

April 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2013

Estimated Enrollment :

60 Patients enrolled

Trial Details

Trial ID

NCT01435694

Start Date

April 1 2011

End Date

June 1 2013

Last Update

January 16 2014

Active Locations (1)

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Physical Medicine and Rehabilitation Department

Ferrara, Ferrara, Italy, 44100