Status:
TERMINATED
Effect of Preoperative Buccal Misoprostol on Blood Loss in Second-trimester Dilation and Evacuation Abortion
Lead Sponsor:
Boston University
Conditions:
Abortion
Blood Loss
Eligibility:
FEMALE
18-50 years
Phase:
PHASE3
Brief Summary
Misoprostol is a medication used extensively in obstetrics and gynecology for its ability to aid in softening the cervix as well as decreasing blood loss after abortion or vaginal delivery. Opinions v...
Detailed Description
This project is a placebo-controlled, double-blinded randomized controlled trial comparing the effect of misoprostol 400mcg buccally to placebo on blood loss in second trimester surgical abortion betw...
Eligibility Criteria
Inclusion
- English or Spanish speaking
- Gestational age between 16 weeks 6 days and 20 weeks 6 days gestation by ultrasound dating on the day of enrollment
- Ultrasound used for dating purposes must be within the last two weeks.
- Women 18-50 years of age undergoing surgical termination of pregnancy
Exclusion
- Spontaneous fetal demise
- Ruptured membranes or intrauterine infection
- Fibroids that significantly distort the uterine shape
- Uterine abnormality such as unicornuate uterus
- Prior transmural myomectomy
- Severe oligohydramnios
- Morbid obesity with BMI\>45
- Inability to place osmotic dilators
Key Trial Info
Start Date :
July 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2012
Estimated Enrollment :
3 Patients enrolled
Trial Details
Trial ID
NCT01436266
Start Date
July 1 2011
End Date
August 1 2012
Last Update
May 30 2017
Active Locations (1)
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1
Boston Medical Center
Boston, Massachusetts, United States, 02118