Status:
UNKNOWN
Probiotics (Lactobacillus Rhamnosus) in Reducing Glucose Intolerance During and After Pregnancy
Lead Sponsor:
Aga Khan University
Conditions:
Glucose Intolerance
Pregnancy
Eligibility:
FEMALE
18-45 years
Phase:
PHASE3
Brief Summary
Introduction: The overall aim of the study is to assess the efficacy of Lactobacillus Rhamnosus in reducing glucose intolerance during and after pregnancy. A second objective of the study is to determ...
Eligibility Criteria
Inclusion
- High risk pregnancy ( presence of more than or equal to 1 of the following)
- Maternal age greater than or equal to 35
- Family history of diabetes among 1st degree relative defined as parents, siblings and children
- Overweight (BMI greater than 23) Women visiting the antenatal clinics during 12-14 weeks of gestation Women with Singleton pregnancy Women whose delivery is planned at the study hospital
Exclusion
- History of GDM ( since in our setting the women are not usually screen for pre- gestational diabetes therefore it is difficult to differentiate between GDM and pre gestational diabetes)
- Known Diabetes mellitus
- Known chronic diseases ( hypothyroidism ,cardiac, renal, rheumatoid arthritis, carcinoma)
- Women maintained on medications such as: corticosteroids, Azathioprin, antiepileptic epileptic drugs.
- Known Poly Cystic Ovarian Syndrome
- Non-residents of Karachi
Key Trial Info
Start Date :
October 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
May 1 2013
Estimated Enrollment :
200 Patients enrolled
Trial Details
Trial ID
NCT01436448
Start Date
October 1 2011
End Date
May 1 2013
Last Update
September 20 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Aga Khan Hospital for Garden
Karachi, Sindh, Pakistan, 74800