Status:
COMPLETED
Assessment of Efficacy of Low Intensity Resistance Training in Women at Risk for Symptomatic Knee Osteoarthritis
Lead Sponsor:
University of Iowa
Collaborating Sponsors:
The American Geriatrics Society
Conditions:
Knee Osteoarthritis
Symptomatic Knee Osteoarthritis
Eligibility:
FEMALE
45-65 years
Phase:
NA
Brief Summary
The purpose of this study is to asses the efficacy of a 4 week low-intensity resistance training program with concurrent application of partial blood flow restriction (PBFR) to the exercising limbs to...
Eligibility Criteria
Inclusion
- Female
- Age 45-65
- BMI greater than or equal to 25 kg/m2, or a history of a knee joint injury or surgery, or knee symptoms (pain, aching, or stiffness) on most of the last 30 days, or knee osteoarthritis
Exclusion
- Resistance training at any time in the last 3 months prior to study
- Bilateral knee replacement
- Lower limb amputation
- Lower limb surgery in the last 6 months that affects walking ability or ability to exercise
- Back, hip or knee problems that affect walking ability or ability to exercise
- Unable to walk without a cane or walker
- Inflammatory joint or muscle disease such as rheumatoid or psoriatic arthritis or polymyalgia rheumatica
- Multiple sclerosis
- Known neuropathy
- Self-report of Diabetes
- Currently being treated for cancer or having untreated cancer
- Terminal illness (cannot be cured or adequately treated and there is a reasonable expectation of death in the near future)
- Peripheral Vascular Disease
- History of myocardial infarction or stroke in the last year
- History of deep venous thrombosis
- Chest pain during exercise or at rest
- Use of supplemental oxygen
- Inability to follow protocol (e.g. lack of ability to attend visits or understand instructions)
- Staff concern for subject health (such as history of dizziness/faintness or current restrictions on activity)
- Concurrent study participation (such as the MOST study)
- Unable to attend more than 2 days within any 1 week or unable to attend 4 or more sessions during the study
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2011
Estimated Enrollment :
45 Patients enrolled
Trial Details
Trial ID
NCT01440972
Start Date
September 1 2011
End Date
November 1 2011
Last Update
December 5 2016
Active Locations (1)
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1
University of Iowa
Iowa City, Iowa, United States, 52242