Status:

COMPLETED

Ingenio Device Algorithm Study

Lead Sponsor:

Boston Scientific Corporation

Conditions:

Sinus Node Disease

AV Block

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of the IVORY Study is to gather data to support global submissions/approvals for some models of the Ingenio device family.

Detailed Description

IVORY is a prospective, multi-center, randomized within-patient, single-blinded study to gather data to support Right Atrial Auto Threshold and RYTHMIQ

Eligibility Criteria

Inclusion

  • Subjects who are willing and capable of providing informed consent to undergo a device implant and to participate in all testing associated with this clinical study;
  • Subjects whose age is 18 or above, or of legal age to give informed consent specific to national law;
  • Subjects indicated for a dual chamber pacemaker or a CRT-P device according to class I or class II indications of the standard ESC or ACC / AHA implant guidelines;
  • Subjects who are planned to be implanted with all leads intended for a specific device type (dual chamber pacemaker: atrial and right ventricular lead, CRT-P: atrial, right and left ventricular lead) or are already implanted with such leads;
  • Subjects who receive or are implanted with a bipolar atrial lead.

Exclusion

  • Women of childbearing potential who are or might be pregnant at the time of the study (method of assessment upon physician's discretion);
  • Enrolled in any other concurrent study, with the exception of local mandatory governmental registries and observational studies/registries that are not in conflict or affect
  • Schedule of procedures for IVORY (i.e. should not cause additional or missed visits);
  • Programming of devices for IVORY per CIP;
  • IVORY outcome (i.e. involve medications that could affect the heart rate of the subject);
  • Conduct of IVORY per GCP / ISO 14 155:2011 / local regulations.
  • Subjects who live at such a distance from the clinic that travels for FU visits at a study center would be unusually difficult or burdensome for the subject;
  • Inability or refusal to comply with the FU schedule;
  • A life expectancy of less than 12 months, per physician discretion;
  • Subjects who are planned to be programmed to a pacing mode other than DDD / DDDR during the study period.

Key Trial Info

Start Date :

October 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

April 1 2013

Estimated Enrollment :

139 Patients enrolled

Trial Details

Trial ID

NCT01441583

Start Date

October 1 2011

End Date

April 1 2013

Last Update

March 21 2024

Active Locations (21)

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Page 1 of 6 (21 locations)

1

Wilhelminenspital

Vienna, Austria, 1160

2

Landesklinikum Wiener Neustadt

Wiener Neustadt, Austria, 2700

3

Clinique Universitaires Saint Luc

Brussels, Belgium, 1200

4

Rigshospitalet Copenhagen

Copenhagen, Denmark, 2100