Status:
COMPLETED
Effect of Pistachio Intake on Insulin Resistance and Type 2 Diabetes Mellitus
Lead Sponsor:
Institut Investigacio Sanitaria Pere Virgili
Collaborating Sponsors:
Western Pistachio Association
Conditions:
Type 2 Diabetes Mellitus
Eligibility:
All Genders
25-65 years
Phase:
NA
Brief Summary
Hypothesis: Chronic intake of pistachios improves glucose metabolism and insulin resistance status thus contributing to decrease the risk of type 2 diabetes mellitus and its associated abnormalities.
Detailed Description
In free-living overweight or obese adult with impaired fasting glucose or impaired glucose tolerance we will compare the effects of a pistachio-rich diet or a Mediterranean Diet on: * Fasting glucose...
Eligibility Criteria
Inclusion
- BMI less than 35 kg/m2.
- Fasting plasma glucose levels between 100 and 125 mg/dl or
- Oral glucose tolerance test of 140 to 199 mg/dl.
Exclusion
- Diabetes mellitus.
- Alcohol, tobacco, or drug abuse.
- Significant liver, kidney, thyroid, or other endocrine diseases.
- Frequent consumption of nuts or known history of allergy to them.
- Use of plant sterol, oral antidiabetic drugs, supplemental use of phyllium, fish oil supplements and multivitamins, vitamin E or other antioxidant supplements.
- Bad dentures, implying difficulty to chew pistachios.
- Being pregnant or wishing to become a pregnant 6 months before or during the study, lactating 6wk before or during the study.
- Following vegetarian or weight loss diets.
- Other medical or social conditions that difficult the compliance to the intervention.
Key Trial Info
Start Date :
September 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2017
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT01441921
Start Date
September 1 2011
End Date
September 1 2017
Last Update
February 11 2019
Active Locations (1)
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1
Human Nutrition Unit, Faculty of Medicine, Rovira i Virgili University
Reus, Tarragona, Spain, 43201