Status:

UNKNOWN

Myocardial Affectation in Patients With Fabry Disease Without Phenotypic Manifestation. Diagnostic Value of Biomarkers

Lead Sponsor:

Francisco Marín Ortuño

Collaborating Sponsors:

Hospital Universitario San Juan de Alicante

Hospital General Universitario Elche

Conditions:

Fabry Disease, Cardiac Variant

Right Ventricular Hypertrophy

Eligibility:

All Genders

Brief Summary

The cardiac variant of the Fabry disease is a rare cardiomyopathy affecting 1/50000 individuals in general population. It is generally diagnosed in advanced stages of the disease, because it presents ...

Detailed Description

Fabry disease is an X-linked recessive disease, affecting lysosomal storage with a variable phenotype characterized by the accumulation of glycosphingolipids in several tissues. It has been described ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria:
  • 20 families with Fabry diagnosed probands, including up to 80 relatives.

Exclusion

    Key Trial Info

    Start Date :

    October 1 2011

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ESTIMATED

    End Date :

    April 1 2013

    Estimated Enrollment :

    120 Patients enrolled

    Trial Details

    Trial ID

    NCT01442350

    Start Date

    October 1 2011

    End Date

    April 1 2013

    Last Update

    September 28 2011

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