Status:
COMPLETED
Iron Absorption From Iron-fortified Fonio Porridge: a Stable Isotope Study
Lead Sponsor:
Wageningen University
Collaborating Sponsors:
International Foundation for Science (IFS)
Conditions:
Iron Deficiency
Eligibility:
FEMALE
18-30 years
Brief Summary
The study sought to investigate the effect of lowering phytic acid in fonio porridge with phytase activity naturally occurring in wheat flour on iron absorption using labelled stable isotopes of iron....
Detailed Description
Objective: To compare the bioavailability of iron in fonio porridge fortified with isotopically enriched \[57Fe\] or \[58Fe\]-ferrous sulfate with and without reducing phytic acid by native phytase in...
Eligibility Criteria
Inclusion
- age 18 - 30 y-old
- apparently healthy
- body weight \< 65 kg (confirmed by anthropometric measurement at recruitment)
- not pregnant (confirmed by pregnancy test)
- not lactating (confirmed by age of last child if any)
- no reported chronic medical illnesses (diabetes, rheumatism, high blood pressure, etc)
- no reported symptoms of malaria in the last 2 months (fever, headache, stomachache, diarrhoea, nausea, vomiting) (confirmed by malaria test)
- No severe anemia (Hb\<90 g/l)
- no intake of vitamin and mineral supplements in the last 2 weeks
- no iron medication or supplementation during the study
- no blood donation in the last 6 months
- no reported allergy to gluten
Exclusion
- body weight (\> 65 kg)
- pregnant
- recent fever malaria
- abnormal CRP level (\>10 mg/l)
- severe anemia (Hb \< 90g/l) and iron deficiency (serum ferritin concentration \< 12 µg/l)
Key Trial Info
Start Date :
September 1 2010
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2011
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT01443832
Start Date
September 1 2010
End Date
February 1 2011
Last Update
November 1 2011
Active Locations (1)
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1
Department Nutrition and Food Science/Univsersity of Abomey calavi
Cotonou, Littoral Department, Benin, 011025