Status:
COMPLETED
Anti-Inflammatory Activities of Grapes in Humans at Risk for Cardiovascular Disease
Lead Sponsor:
USDA, Western Human Nutrition Research Center
Conditions:
Obesity
Inflammation
Eligibility:
All Genders
20-60 years
Phase:
NA
Brief Summary
The goal of the study is to determine whether grape consumption can reduce the risk of cardiovascular disease by reducing the presence of inflammatory molecules and positively altering cholesterol lev...
Detailed Description
Obese individuals are at high risk for the development of hypertension and cardiovascular disease. Adipose tissue is a major source of pro-inflammatory molecules which can promote the development of a...
Eligibility Criteria
Inclusion
- BMI 30 - 45 kg/m2
- Commitment to the dietary intervention and scheduled testing
Exclusion
- Subjects will be excluded from this study if their blood cell counts or blood chemistry profiles are outside of the normal range
- smoking or use of tobacco products
- drink more than one alcoholic beverage per day (1 oz. distilled liquor, 3 oz. wine, or 12 oz. beer)
- taking cholesterol-lowering medications
- taking steroids for asthma or other inflammatory states
- taking thyroid-regulating drugs
- taking over-the counter weight loss products
Key Trial Info
Start Date :
October 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT01443884
Start Date
October 1 2009
End Date
October 1 2011
Last Update
December 12 2011
Active Locations (1)
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1
USDA, ARS, Western Human Nutrition Research Center
Davis, California, United States, 95616