Status:
COMPLETED
Eyelid Warming Technology for Meibomian Gland Dysfunction
Lead Sponsor:
Singapore National Eye Centre
Collaborating Sponsors:
Singapore Eye Research Institute
National University of Singapore
Conditions:
Meibomian Gland Dysfunction
Eligibility:
All Genders
21-90 years
Phase:
NA
Brief Summary
Meibomian gland dysfunction (MGD), an extremely common clinical condition (seen in more than half of some Asian populations), affects the lipid producing meibomian glands in the eyelids. One function ...
Detailed Description
Study Objectives and Purpose: 1. A primary purpose of the study is to compare the efficacy of novel eyelid warming devices (Blephasteam and EyeGiene) for treatment of meibomian gland dysfunction by o...
Eligibility Criteria
Inclusion
- Eyelids must present with blocked meibomian gland openings (plugs), at least 1 visible MG plug in the 4 eyelids, or discernable change in consistency of meibum when MG expressed in upper or lower eyelids.
- At least one out of 8 questions on dry eye symptoms is answered with often or all the time (Appendix C, Questionnaire modified after Schein et al.,1997).
- Eyes should not show any other ocular surface pathology which required more treatment than eye lubricant and conventional eyelid hygiene.
Exclusion
- Known history of thyroid disorders (diagnosed by physician).
- No ocular surgery within the previous 6 months and LASIK within the previous 1 year.
- Any intake of central nervous system and hormonal drugs within last 30 days and inability to withhold such drugs for at least 6 weeks.
- Active ocular infection or pterygium.
- Anticipated necessity to wear contact lens in the duration of the study.
- Living in the same household as another participant of the study.
- Any other specified reason as determined by clinical investigator, for example, the need to use any treatment or eyedrops (eg. Restasis) not permitted by the study.
Key Trial Info
Start Date :
December 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2013
Estimated Enrollment :
75 Patients enrolled
Trial Details
Trial ID
NCT01448369
Start Date
December 1 2011
End Date
December 1 2013
Last Update
June 10 2014
Active Locations (1)
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1
Singapore National Eye Centre/ Singapore Eye Research Institute
Singapore, Singapore, Singapore, 168751