Status:
COMPLETED
Surgical Site Infection Study
Lead Sponsor:
Children's Hospital of Philadelphia
Conditions:
Cava-pulmonary Anastomosis
Eligibility:
All Genders
3-6 years
Brief Summary
The purpose of this study is to investigate the pharmacokinetics of cefazolin using both plasma and microdialysate sampling methods in children with single ventricle physiology undergoing their second...
Detailed Description
This study aims to sample interstitial fluid (IF) of infants undergoing superior cava-pulmonary anastomosis (either Glenn or Hemi-Fontan) cardiac surgical procedures who receive cefazolin as their sur...
Eligibility Criteria
Inclusion
- Males or females with single ventricle physiology undergoing their second palliation procedure (typically performed between 3-6 months of age)
- Use of cefazolin as the prophylactic antibiotic during the operation
- Written informed consent provided by the parent or legal guardian
Exclusion
- Use of prophylactic antibiotic other than cefazolin during the operation
- Anatomic or other abnormalities of the upper arm that would preclude insertion of a microdialysis catheter
- Known renal or hepatic function
Key Trial Info
Start Date :
September 1 2011
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 1 2014
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT01449669
Start Date
September 1 2011
End Date
February 1 2014
Last Update
February 10 2014
Active Locations (0)
Enter a location and click search to find clinical trials sorted by distance.
No Results Found
We couldn’t find results for the location/zipcode entered or within the selected range. Please check your input or adjust your search.