Status:
COMPLETED
The Effectiveness of Enough Steroids as Inducement Therapy in Minimal Change Disease-like IgA Nephropathy
Lead Sponsor:
Nanjing University School of Medicine
Conditions:
IgA Nephropathy
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
This is a single center,prospective,no-controlled clinical trial
Detailed Description
1. The complete remission of enough steroids as inducement therapy in adult minimal change disease-like IgA nephropathy patients 2. The safety of enough steroids as inducement therapy in adult minimal...
Eligibility Criteria
Inclusion
- Female or male patients aged between 18 to 65 years
- Renal biopsy was used to diagnose IgA nephropathy
- Patients with 24h proteinuria 3.5g and serum albumin concentration lower than 30g/L
Exclusion
- Patients with serum creatinine ≥ 3 mg/dl or eGFR \< 30ml/min per 1.73 m2
- urine RBC \> 1 million/ml
- Patients who have received treatment of enough steroids for more than 12 weeks
- patients with secondary IgA
- Patients who have impaired liver function,with ALT/GPT or AST/GOT twice more than the normal upper limit or who have active hepatitis
- Patients with 2 type diabetes or obesity, whose BMI is more than 28kg/m2
Key Trial Info
Start Date :
March 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
May 1 2012
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT01451710
Start Date
March 1 2011
End Date
May 1 2012
Last Update
July 10 2012
Active Locations (1)
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1
Research Institute of Nephrology, Jinling Hospital, Nanjing University School of Medicine
Nanjing, Jiangsu, China