Status:
COMPLETED
Progressive Metabolic Adaptations to Low Intensity Exercise Training and Weight Loss
Lead Sponsor:
University of Michigan
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Obesity
Eligibility:
All Genders
18-45 years
Phase:
NA
Brief Summary
the investigators first aim is to determine the effect of low intensity exercise (without weight loss) on insulin sensitivity, muscle lipid metabolism, and factors regulating these processes in skelet...
Eligibility Criteria
Inclusion
- body mass index \[BMI\]: 30-45 kg/m2; All women must be pre-menopausal; Non-exerciser (no regularly planned exercise/physical activity)
Exclusion
- Hematocrit ≤ 34%; Fasting plasma glucose concentration ≥ 125 mg/dL; Weight instability ≥ ±5 lbs in past month; Taking medications known to affect lipid and/or glucose metabolism; evidence and/or history of cardiovascular or frank metabolic diseases; pregnancy or actively breast feeding
Key Trial Info
Start Date :
July 1 2011
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
July 18 2014
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT01452074
Start Date
July 1 2011
End Date
July 18 2014
Last Update
March 21 2022
Active Locations (1)
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1
Michigan Clincal Research Unit
Ann Arbor, Michigan, United States, 48109