Status:
COMPLETED
Repetitive Transcranial Magnetic Stimulation in Postpartum Depression
Lead Sponsor:
University of Sao Paulo General Hospital
Conditions:
Depression, Postpartum
Eligibility:
FEMALE
18-36 years
Phase:
PHASE2
Brief Summary
Several factors characterize repetitive transcranial magnetic stimulation (rTMS) as a strategic aid in the treatment of postpartum depression. However, up to current days there have been no studies e...
Detailed Description
Transcranial magnetic stimulation is a noninvasive technique that can influence specific areas of the brain and has very few side effects. The treatment with transcranial magnetic stimulation require...
Eligibility Criteria
Inclusion
- major depression with a puerperal onset, according to the criteria of the DSM-IV-R (APA, 2000), as well as through a structured clinical interview (SCID-1/P v 2.0)
- baseline score of at least 14 points on the Hamilton Depression rating Scale-17 items
- baseline score of at least 13 points on the Edinburgh Postnatal Depression Scale.
- range = 18-36 years
- women who had given birth 1-6 months
- any pharmacological treatment other than clonazepam (1 mg/day)
Exclusion
- comprised ferromagnetic metallic implants
- pacemakers
- previous neurosurgery
- history of seizures
- major head trauma
- alcoholism
- drug addiction
- any psychiatric or neurological disorder other than depression and anxiety
- psychotic depression
- suicidal propensities
Key Trial Info
Start Date :
August 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
September 1 2009
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT01452321
Start Date
August 1 2007
End Date
September 1 2009
Last Update
October 14 2011
Active Locations (1)
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1
Department and Institute of Psychiatry, General Hospital, University of Sao Paulo medical school
São Paulo, São Paulo, Brazil