Status:

COMPLETED

Measuring Free-living Energy Expenditure Using Direct Calorimetry

Lead Sponsor:

University of Colorado, Denver

Collaborating Sponsors:

University of Alabama at Birmingham

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

Conditions:

Temperature

Clothing

Eligibility:

All Genders

18+ years

Brief Summary

Although instruments such as pedometers and heart rate monitors are helpful for those who use exercise to maintain their weight, they do not actually measure calories expended, which is a critical pie...

Detailed Description

Current approaches to measuring total daily energy expenditure (TDEE) in free-living individuals are limited by cost, accuracy, and lack of sensitivity to specific activities. Accurate, reliable, and ...

Eligibility Criteria

Inclusion

  • These studies will be conducted in Denver. CO. Eligible participants will be those local to the University.
  • Study #1 (Effects of clothing and temperature)
  • Inclusion Criteria
  • Body mass index (BMI) 19-25 kg/m2
  • Age 18-45 years
  • Exclusion criteria
  • Self-reported acute or chronic disease (e.g. diabetes, heart disease, thyroid disease)
  • Tobacco use (cigarettes, cigars, or chewing tobacco) within the past 6 months
  • Females who are or who were recently (past year) pregnant or lactating.
  • Resting diastolic blood pressure \> 100 mm HG or resting systolic blood pressure \> 160 mm HG
  • Contra-indications to exercise (e.g. orthopedic limitations)
  • Study #2 (Effect of age, sex, and adiposity)
  • Inclusion Criteria • Age ≥18 yrs
  • Exclusion criteria
  • Weight \> 300 lbs (due to DXA limitations)
  • Self-reported acute or chronic disease (diabetes, heart disease, thyroid disease)
  • Tobacco use (cigarettes, cigars, or chewing tobacco) within the past 6 months
  • Females who are or who were recently (past year) pregnant or lactating.
  • Resting diastolic blood pressure \> 100 mm HG or resting systolic blood pressure \> 160 mm HG
  • Contra-indications to exercise (e.g. orthopedic limitations)
  • Study #3 (Doubly labeled water)
  • Inclusion Criteria
  • • Age ≥18 yrs
  • Exclusion criteria
  • Weight \> 300 lbs (due to DXA limitations)
  • Self-reported acute or chronic disease (diabetes, heart disease, thyroid disease)
  • Tobacco use (cigarettes, cigars, or chewing tobacco) within the past 6 months
  • Females who are or who were recently (past year) pregnant or lactating

Exclusion

    Key Trial Info

    Start Date :

    January 1 2012

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    January 1 2016

    Estimated Enrollment :

    39 Patients enrolled

    Trial Details

    Trial ID

    NCT01454882

    Start Date

    January 1 2012

    End Date

    January 1 2016

    Last Update

    January 11 2016

    Active Locations (1)

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    Page 1 of 1 (1 locations)

    1

    University of Colorado Denver Anschutz Medical Campus

    Aurora, Colorado, United States, 80045