Status:

COMPLETED

A Study Of Oral CP-690,550 As A Maintenance Therapy For Ulcerative Colitis

Lead Sponsor:

Pfizer

Conditions:

Ulcerative Colitis

Eligibility:

All Genders

18+ years

Phase:

PHASE3

Brief Summary

The study proposes to assess whether compared to placebo, CP-690,550 is effective, safe, and tolerable maintenance therapy in subjects with Ulcerative Colitis (UC). The study proposes to assess whethe...

Eligibility Criteria

Inclusion

  • Subjects who met study entry criteria and completed 8-week induction treatment from Study A3921094 or A3921095
  • Subjects who achieved clinical response in Study A3921094 or A3921095
  • Women of childbearing potential must test negative for pregnancy prior to study enrollment
  • Subjects who are willing and able to comply with scheduled visits, treatment plan, laboratory tests, and other study procedures
  • Evidence of a personally signed and dated informed consent document(s) indicating that the subject (or a legally acceptable representative) has been informed of all pertinent aspects of the study.

Exclusion

  • Subjects who had major protocol violation (as determined by the Sponsor) in Study A3921094 or A3921095
  • Presence of indeterminate colitis, microscopic colitis, ischemic colitis, infectious colitis, or clinical findings suggestive of Crohn's disease
  • Subjects who have had surgery for UC or in the opinion of the investigator, are likely to require surgery for UC during the study period.

Key Trial Info

Start Date :

July 20 2012

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

May 27 2016

Estimated Enrollment :

593 Patients enrolled

Trial Details

Trial ID

NCT01458574

Start Date

July 20 2012

End Date

May 27 2016

Last Update

May 18 2017

Active Locations (275)

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Page 1 of 69 (275 locations)

1

Internal Medicine Center, LLC

Mobile, Alabama, United States, 36608

2

Springhill Memorial Hospital (Endoscopy Only)

Mobile, Alabama, United States, 36608

3

UCSD Health System - Investigational Drug Pharmacy - Moores Cancer Center

La Jolla, California, United States, 92037-0845

4

UCSD Medical Center

La Jolla, California, United States, 92093

A Study Of Oral CP-690,550 As A Maintenance Therapy For Ulcerative Colitis | DecenTrialz