Status:

COMPLETED

Effectiveness of rTMS With Double-Cone-Coil in Patients With Major Depression

Lead Sponsor:

University of Regensburg

Conditions:

Depression

Eligibility:

All Genders

18-75 years

Phase:

NA

Brief Summary

Repetitive Transcranial Magnetic Stimulation (rTMS) is used to modulate the neuronal excitability in patients with depression. In the present study the investigators will examine whether medial fronta...

Detailed Description

Depression is a common mental disorder that presents with depressed mood, loss of interest, feelings of guilt or low self-worth, disturbed sleep or appetite, low energy levels and poor concentration. ...

Eligibility Criteria

Inclusion

  • Episode of depression (unipolar or bipolar)( ICD-10)
  • Female or male between 18 and 70 years old
  • Skills to participate in all study procedures
  • 18 or more points in the Hamilton rating scale or depression
  • Stable antidepressant drugs
  • Written informed consent

Exclusion

  • Clinically relevant unstable internal or neurological comorbidity
  • Evidence of significant brain malformations or neoplasm, head injury
  • Cerebral vascular events
  • Neurodegenerative disorders affecting the brain or prior brain surgery
  • Metal objects in and around body that can not be removed
  • Pregnancy
  • Alcohol or drug abuse
  • Epilepsy or a pathological EEG
  • Heart pacemaker
  • High dose tranquillizers

Key Trial Info

Start Date :

April 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2013

Estimated Enrollment :

45 Patients enrolled

Trial Details

Trial ID

NCT01460758

Start Date

April 1 2011

End Date

November 1 2013

Last Update

April 28 2014

Active Locations (1)

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University of Regensburg- Dept of Psychiatry

Regensburg, Germany