Status:

COMPLETED

Continuous Positive Airway Pressure and Oral Appliances Treatments in Mild Obstructive Sleep Apnea

Lead Sponsor:

Associação Fundo de Incentivo à Pesquisa

Conditions:

Mild Obstructive Sleep Apnea Syndrome

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Treatment response of mild obstructive sleep apnea (OSA) to continuous positive airway pressure (CPAP) therapy and oral appliance (OA) is still controversial. The aim of this study is to evaluate the ...

Eligibility Criteria

Inclusion

  • Both genders;
  • body mass index lower than 35Kg/m2;
  • age between 18 and 65 years old;
  • polysomnographic and clinical diagnosis of mild apnea (apnea-hypopnea index of 5 or more events per hour of sleep and less than 15 and minimum mandibular protrusion of 7mm.

Exclusion

  • Unsatisfactory dental conditions (active periodontal disease, extensive caries or insufficient teeth for appliance content);
  • temporomandibular disorders (chronic joint or muscle disease); central apnea; claustrophobia and severe otorhinolaryngologic diseases (severe nasal septal deviation, marked hypertrophy of nasal turbinates, hypertrophy of tonsils and/or adenoids sharp);
  • excessive use of alcohol and psychoactive drugs;
  • clinical, neurological or psychiatric decompensated diseases;
  • others sleep diseases and previous obstructive sleep apnea treatment.

Key Trial Info

Start Date :

October 1 2011

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2019

Estimated Enrollment :

79 Patients enrolled

Trial Details

Trial ID

NCT01461486

Start Date

October 1 2011

End Date

November 1 2019

Last Update

November 13 2019

Active Locations (1)

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Associação Fundo de Incentivo à Pesquisa

São Paulo, São Paulo, Brazil, 04024-002